Friday 15 August 2008

Anemia Of Chronic Disease: An Adaptive Response?


The anemia of chronic disease english hawthorn be a beneficial, adaptative response to the underlying disease, rather than a negative effect of the illness, postulates an analysis article in CMAJ, http://www.cmaj.ca/press/pg333.pdf.



The authors argue that anaemia may be beneficial to patients with inflammatory disease, and advocate restraint in treating mild to check forms of anemia.



"The general assumption is that anemia is a disorder and that patients would be better sour without it," state the authors.



However, they suggest that anemia of chronic disease has the characteristics of an adaptative physiologic response, and their review of the literature shows that mortality appears to increase when treatment, given to raise haemoglobin levels, overrides mild to moderate anemia of chronic disease. They call for better characterization of the cause of individual patients' anemia in future trials of anaemia treatment, and careful monitoring of adverse outcomes, including mortality, if patients with anemia of chronic disease are included in such trials.



Source:

Jennifer Paterson
Canadian Medical Association Journal



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Thursday 7 August 2008

The Sisterhood of the Traveling Pants 2






The Sisterhood of the Traveling Pants 2
Director: Sanaa Hamri
Stars: America Ferrera, Blake Lively, Amber Tamblyn, Alexis Bledel
Classification: PG13
Rating: *** (out of five)

There�s a telling, tense scene early in Sisterhood 2 where America Ferrera, Blake Lively, Amber Tamblyn and Alexis Bledel gather to renew the ritual of the travelling pants. The bloomers (as you would experience if you�re familiar with the first movie or Ann Brashares� series of novels) miraculously fit all four friends. They put across them turned to ane another and stay shut down at the same time. It�s a common bond for the four unlikely but likeable friends as they have separate paths to adulthood.

But hang on � those jeans (and those friendships) appear to be fading fast. The ritual has become slow for leash of them, and it looks like the BFFs might be DOA.

And so Sisterhood 2 explores how the foursome handle more and more adult responsibilities in their ever-separating lives, all the while struggling to maintain their puerility friendships.

There�s a lot of life packed into the four lives: A gestation scare, relationship issues, coping with death, family bonds, new love vs. previous flame, a new career � the stories of their lives are intercut, and Hamri generally does a good job of giving each story the right measure of elbow room to advertize the patch along. Two of the lead actors really shine: Blake Lively (Gossip Girl) is a striking presence, radiating from the filmdom in every scene she�s in. America Ferrera (Ugly Betty) seems to own perfected the Cinderella/underdog thing. It�s out of the question not to cheer for her.

At the end of the day, Sisterhood 2 is a big recreate � hurrah for the friends as everything works out (of course).

In reality, near of us do variety and outgrow our puerility friendships. That catchup telephone set call, electronic mail, lunch, or coffee date never comes.

Sisterhood 2 gives us the chance to vicariously stay shut down to everyone we dearest.








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